PD-1 anticorps (PE-Cy5.5)

N° du produit ABIN7673970

L’anticorps Rat Monoclonal anti-PD-1 a été validé pour FACS. Il convient pour détecter PD-1 dans des échantillons de Souris.

Aperçu rapide pour PD-1 anticorps (PE-Cy5.5) (ABIN7673970)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est conjugé à/à la PE-Cy5.5

Application: Flow Cytometry (FACS)

Clone: 29F-1A12

Détail du produit anti-PD-1 anticorps (PE-Cy5.5)

Fonction: PE-Cy5.5 Anti-Mouse CD279/PD-1 Antibody

Purification: 0

Pureté: 0

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279

Sujet:

Synonyms: Programmed Death-1|PD-1

Background: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Poids moléculaire: 0

ID gène: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints